| 引用本文: | 李凤前;陆彬;陈文彬1.肺靶向汉防己甲素缓释微囊的安全性评价[J].中国现代应用药学,2002,(6):478-480. |
| Li Fengqian, Lu Bin , Chen Wenbin 1.Evaluation of the safety of tetrandrine loaded sustained release microcapsules for lung targeting[J].Chin J Mod Appl Pharm(中国现代应用药学),2002,(6):478-480. |
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| 摘要: |
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| 关键词: 汉防己甲素 微囊 急性毒性 体外溶血 刺激性 过敏性 |
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| 基金项目:九五攻关国家重点项目批准号 96-906-02-17 |
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| Evaluation of the safety of tetrandrine loaded sustained release microcapsules for lung targeting |
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Li Fengqian, Lu Bin , Chen Wenbin 1
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| Abstract: |
| OBJECTIVE:To evaluate the safety of tetrandrine (TET) loaded bovine serum albumin microcapsules(TET MC). METHOD:"Spray drying thermal denaturation" technique was used to prepare TET MC. The acute and long term toxicity tests, hemolysis test in vitro, |
| Key words: tetrandrine, microcapsules, acute toxicity, hemolysis in vitro , stimulation, allergy |
