引用本文: | 郭勇;谢长生;冯正权.复方藤梨根制剂体外对MDR细胞株K562/ADR和K562/VCR细胞积聚和外排阿霉素(ADR)的影响研究[J].中国现代应用药学,2002,(4):268-272. |
| Guo Yong, Xie Changshang, Feng Zhengquan.The study of effects on accumulation and efflux of intracellular adrimycine with FFTLG for multidrug resistant cell lines K562/ADR and K562/VCR in vitro[J].Chin J Mod Appl Pharm(中国现代应用药学),2002,(4):268-272. |
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关键词: 多药耐药 复方中药 作用机制 |
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基金项目:国家中医药管理局课题 (编号 :95C015) ;获浙江省中医药科技进步二等奖 |
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The study of effects on accumulation and efflux of intracellular adrimycine with FFTLG for multidrug resistant cell lines K562/ADR and K562/VCR in vitro |
Guo Yong, Xie Changshang, Feng Zhengquan
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OBJECTIVE:To investigate the mechanism of enhance sensitivity for chemotherapy of cancer with FFTLG. METHOD:Using tetrazolium dye assay,reversal effect of FFTLG on multidrug resistant cell lines K562/ADR and K562/VCR. The accumulation and efflux of intrac |
Key words: multidrug resistance, compound Chinese medicine, mechanism |