| 引用本文: | 封淑华;王丽萍;王俊峰;刘红莉;刘丽芳1;马庆1.UV法测定盐酸二甲双胍肠溶片的释放度和含量[J].中国现代应用药学,2001,(6):463-465. |
| Feng Shuhua, Wang Liping, Wang Junfeng, et al.Determination of metformin hydrochloride enteric-coated tablets by UV[J].Chin J Mod Appl Pharm(中国现代应用药学),2001,(6):463-465. |
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| 摘要: |
| 目的:建立盐酸二甲双胍肠溶片的质量标准。方法:采用UV法测定盐酸二甲双胍肠溶片在酸及缓冲液中的释放度及含量。结果:在选定的波长处,辅料及肠溶衣对测定无干扰,释放度平均回收率99.0 % ,含量平均回收率99.9%。结论:测定方法简便,结果可靠,可作为该制剂质量控制标准 |
| 关键词: 盐酸二甲双胍肠溶片 释放度 含量测定 紫外分光光度法 |
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| Determination of metformin hydrochloride enteric-coated tablets by UV |
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Feng Shuhua, Wang Liping, Wang Junfeng, et al
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| Abstract: |
| OBJECTIVE: Estabilish a method for the quality control of metformin hydrochloride enteric coated tablets. METHOD: The rate of release and content of metformin hydrochloride enteric coated tablets were determinated by UV. RESULTS: The excipient is not in |
| Key words: Metformin hydrochloride enteric coated tablets, in vitro release, determination of content, UV |
