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摘要: |
目的:系统了解基质金属蛋白酶的生物作用,促进其深入研究及发展。方法:综述近几年国内外对MMP生物抑制剂、合成抑制剂的开发及作用机理的研究情况。结果:目前对MMP抑制剂的研究还处于临床试验及探索阶段。结论:MMP抑制剂正被开发为一种新型的抗血管生成剂 |
关键词: 基质金属蛋白酶 MMP抑制剂 肿瘤转移 |
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Consulting the study of matrix metalloproteinase inhibitors |
Tao Xuefen,Hu Yongzhou
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Abstract: |
OBJECTIVE:To systematically review the physiological functions of matrix metalloproteinases(MMP),and promote its further study and development. METHOD:Consulting the literatures both in domestic and foreign ,the development and action mechanism study of p |
Key words: matrix metalloprotein MMP inhibitors tumor transfer |