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关键词: 吉非罗齐 正丁基锂 合成 |
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Synthesis of gemfibrozil |
Lu Jinrong(Lu JR),Ma Ying(Ma Y)
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OBJECTIVE:To synthesize gemfibrozil and optimize the process.METHOD:Gemfibrozil was synthesized from 3-(2,5-xylyloxyl) propyl chloride which was reacted with sodium isobutyrate first and then react with n butyllithium.3-(2,5-xylyloxyl) propyl chloride wa |
Key words: gemfibrozil,n-butyllithium,synthesis |