引用本文: | 朱卡林;洪缨;楼宜嘉.环磷酰胺对大鼠早期胚胎发育里程的影响[J].中国现代应用药学,1999,(5):1-3. |
| Zhu Kalin(Zhu KL),Hong Ying(Hong Y),Lou Yijia(Lou YJ).Effects of cyclophosphamide on early rat embryo developmental landmark[J].Chin J Mod Appl Pharm(中国现代应用药学),1999,(5):1-3. |
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摘要: |
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关键词: 环磷酰胺 胚泡 发育毒性 药源性异常 |
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基金项目:国家自然科学基金;浙江省自然科学基金 |
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Effects of cyclophosphamide on early rat embryo developmental landmark |
Zhu Kalin(Zhu KL),Hong Ying(Hong Y),Lou Yijia(Lou YJ)
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Abstract: |
OBJECTIVE:To study the effects of alkylate on the developmental mileage of early mammal embryos and the possible mechanism.METHOD:Pregnant rats on d3 of gestation were given ip cyclophosphamide(Cyc)10,20,40 mg/kg .On d4,the blastulation,the developmenta |
Key words: cyclophosphamide,blastocyst,developmental toxicity,drug-induced abnormalities |