| 引用本文: | 梁高林;胡名扬;王博诚.帕米膦酸二钠的合成[J].中国现代应用药学,1999,(2):37-38. |
| Liang Gaolin(Liang GL),Hu Mingyang(Hu MY),Wang Bocheng(Wang BC).Synthesis of disodium 3-amino-1-hydroxy-propilidene-1,1-diphosphonate[J].Chin J Mod Appl Pharm(中国现代应用药学),1999,(2):37-38. |
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| 摘要: |
| 目的:合成二钠3 -氨基-1 -羟基-亚丙基-二膦酸盐(帕米膦酸二钠)。方法:有、无溶剂的两种合成路线,并对工艺进行改进。所得产物经元素分析,红外光谱,质谱等分析确证结构。结果:两种路线均可合成目标化合物。路线A收率高于路线B。结论:溶剂的加入使本反应体系均一,有利于产物生成 |
| 关键词: 合成 帕米膦酸二钠 |
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| Synthesis of disodium 3-amino-1-hydroxy-propilidene-1,1-diphosphonate |
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Liang Gaolin(Liang GL),Hu Mingyang(Hu MY),Wang Bocheng(Wang BC)
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| Abstract: |
| OBJECTIVE:To synthesize disodium 3-amino-1-hydroxy-propilidene-1,1-diphosphonate.METHOD:Two processes had been improved(with or within solvent).Chemical structures of products were confirmed by element analysis,IR,MS,et al.RESULTS:Both of the two processe |
| Key words: synthesize,diphosphonate |
