| 引用本文: | 孙志忠;郝文辉;段树红;张素萍;邢有权;郑庆波1.木犀草素的半合成[J].中国现代应用药学,1999,(1):30-31. |
| Sun Zhizhong(Sun ZZ),Hao Wenhui(Hao WH),Duan Shuhong(Duan SH),et al.Partial-synthesis of Luteoin[J].Chin J Mod Appl Pharm(中国现代应用药学),1999,(1):30-31. |
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| 摘要: |
| 目的:半合成具有止咳、祛痰及消炎作用的木犀草素。方法:从陈皮中提取橙皮苷,橙皮苷再经水解、脱甲基、脱氢三步合成木犀草素。结果:三步总收率为4 5.9% ,同时还以较好收率合成了双氢黄酮化合物:橙皮素2和圣草酚3。结论:该工艺原料易得、工艺简单、收率高。 |
| 关键词: 半合成 木犀草素 橙皮苷 橙皮素 圣草酚 |
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| Partial-synthesis of Luteoin |
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Sun Zhizhong(Sun ZZ),Hao Wenhui(Hao WH),Duan Shuhong(Duan SH),et al
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| Abstract: |
| OBJECTIVE:Luteoin 4,which relieves a cough,makes expectoration easy and has antiphlogosis,was partial-synthesized.METHODS:Three steps including hydrolysis,demethylation and dehydrogenation from hesperidin,which was extracted from citrus,was reported in th |
| Key words: partial-synthesis,luteoin,hesperidin,hesperitin,eridictyol |
