细胞色素P450 2C19单碱基突变位点CYP2C19m1的分析

赵鲁杭;孙红颖;郑妮娜;李菊花;姚彤炜;陈枢青

引用本文:	赵鲁杭;孙红颖;郑妮娜;李菊花;姚彤炜;陈枢青.细胞色素P450 2C19单碱基突变位点CYP2C19m1的分析[J].中国现代应用药学,1998,(3):36-38.
	Zhao Luhang(Zhao LH),Sun Hongying(Su HY),Zheng Nina(Zheng NN),et al.Analysis of single base mutation of cytochrome P450 2C19 allele CYP2C19m1[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(3):36-38.

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细胞色素P450 2C19单碱基突变位点CYP2C19m1的分析
赵鲁杭;孙红颖;郑妮娜;李菊花;姚彤炜;陈枢青

作者	单位
赵鲁杭;孙红颖;郑妮娜;李菊花;姚彤炜;陈枢青

摘要:

关键词: 细胞色素P4502C19(CYP2C19) CYP2C19ml 基因分型等位基因特异扩增法(ASA)

DOI：

分类号:

基金项目:浙江省自然科学基金资助课题第396473号

Analysis of single base mutation of cytochrome P450 2C19 allele CYP2C19m1

Zhao Luhang(Zhao LH),Sun Hongying(Su HY),Zheng Nina(Zheng NN),et al

Abstract:

OBJECTIVE: Cytochrome P450 2C19 enzyme deficiency was mainly caused by CYP2C19ml allele.It was said more than 83 % of poor metabolizers were due to the existence of this allele. This study was aimed to set up an efficient PCR procedure to analyse this all

Key words: Cytochrome P450 2C19(CYP2C19) CYP2C19ml Genotyping Allele - specific amplification