引用本文: | 张云;刘国卿;任文华1;罗亚东2.阿仑膦酸钠的一般药理研究[J].中国现代应用药学,1998,(3):1-3. |
| Zhang Yun( Zhang Y),Ren Wenhua(Ren WH),Luo Yadong(Luo YD),et al.General pharmacological studies of alendronate[J].Chin J Mod Appl Pharm(中国现代应用药学),1998,(3):1-3. |
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摘要: |
ig阿仑膦酸钠2.5,5和10mg/kg对小鼠的协调运动和自主活动,麻醉猫的呼吸频率、呼吸深度、平均动脉压、心率及心电图无明显影响;iv 5mg/kg对麻醉猫的呼吸、血压、心率及心电图亦无明显影响。iv 10mg/kg对麻醉猫的血压有短暂降低作用,对呼吸、心率及心电图无显著改变。 |
关键词: 阿仑膦酸钠 药理学 自主活动 血压 ECG |
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General pharmacological studies of alendronate |
Zhang Yun( Zhang Y),Ren Wenhua(Ren WH),Luo Yadong(Luo YD),et al
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Abstract: |
It was found that alendronate(2.5,5 and 10mg/kg,ig) had no obvious effects on the coordinative motor performance and spontaneous activity in conscious mice, the rate and amplitude of respiration, mean blood pressure, heart rate and ECG in anaesthetized ca |
Key words: alendronate,pharmacology,spontaneous activity,blood pressure,ECG |