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摘要: |
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关键词: 氯霉素 遗传毒性 胚泡 微核 |
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基金项目:国家自然科学基金!39470836 |
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Genetic Toxicity of Chloramphenicol to Rat Preimplant Blastocysts in vivo |
Xu Qing;Lou Yija;Zhang Lijin
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Abstract: |
To evaluate the genetic toxicity of chloramphenicol on preimplanted blastocysts .Wistar rats were treated with chloramphenicol (ip, 65mg, 165mg and 330mg/kg)on d3 of gestationin rats. Blastocysts were collected on d4 and evaluated for micronuclei, blasto |
Key words: chloramphenicol genetic toxicity, blastocyst micronucleus |