|
| 摘要: |
| 对二种不同重排法合成萘普生进行了比较,其中,氧化锌催化重排法收率高,醋酸钾催化重排收率中等。并改进了澳代,重排条件,简化了工艺。 |
| 关键词: 萘普生 合成 溴代 缩酮 重排 |
| DOI： |
| 分类号: |
| 基金项目: |
|
| The Comparison of Two Synthetic Methods of dl-Naproxen via 1.2-Aryl Rearrangement |
|
Hu Yongzhou Cao Yaqin
|
| Abstract: |
| Two synthetic methods of dl-naproxen via 1. 2-Aryl rearrangement were compared. Naproxen was obtained in high yield when ZnO was used as catalyst and in middle yield when KOAC was used. The modified procedures were made in bromination and rearrangement. T |
| Key words: Napoxen Synthesis Bromination Ketalization Rearrangement. |
