| 引用本文: | 沈薇,石晓峰,王东东,滕有斌,刘东彦.正交试验优选雪松松针中莽草酸的提取工艺[J].中国现代应用药学,2011,28(9):831-834. |
| SHEN Wei,SHI Xiaofeng,WANG Dongdong,TENG Youbin,LIU Dongyan.Optimization of the Extracting Process of Shikimic Acid from Pine Needles of Cedrus Deodara (Roxb.) G. Don by Orthogonal Experiment[J].Chin J Mod Appl Pharm(中国现代应用药学),2011,28(9):831-834. |
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| 摘要: |
| 目的 优选雪松松针中莽草酸的最佳提取工艺。方法 采用L9(34)正交试验设计，以莽草酸的含量为指标，以液料比、浸泡时间、提取时间为因素，优化雪松松针中莽草酸的提取工艺。结果 最佳提取工艺为加20倍量的水，浸泡0.5 h，加热回流2 h。在最佳工艺条件下，提取的莽草酸含量为3.58%。结论 优选得到的提取工艺简单、稳定、可行。 |
| 关键词: 雪松松针 正交试验设计 提取工艺 莽草酸 |
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| 基金项目:甘肃省技术研究与专项计划项目(0709TCYA022)；甘肃省卫生厅科研计划项目(WST07-02) |
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| Optimization of the Extracting Process of Shikimic Acid from Pine Needles of Cedrus Deodara (Roxb.) G. Don by Orthogonal Experiment |
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SHEN Wei1, SHI Xiaofeng1, WANG Dongdong2, TENG Youbin1, LIU Dongyan2
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1.Gansu Academy of Medical Science, Lanzhou 730050, China;2.School of Pharmacy, Lanzhou University, Lanzhou 730000, China
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| Abstract: |
| OBJECTIVE To optimize the extraction technology and condition of shikimic acid from pine needles of Cedrus deodara (Roxb.) G. Don. METHODS The extraction technology of shikimic acid was optimized by L9(34) orthogonal experiment with the contents of shikimic acid as index, and with the ratio of raw material to liquid, soaking time and extraction time as factors. RESULTS The optimal extracting process was adding 20 times of water, soaking 0.5 h, reflux 2 h. Under the conditions, the content of shikimic acid was 3.58%. CONCLUSION The optimal extracting process is simple, stable and practical. |
| Key words: pine needles of Cedrus deodara (Roxb.) G. Don orthogonal experiment extracting process shikimic acid |
