| 引用本文: | 邓双炳,菅晓勇,任启生,宋新荣,叶连宝,邹国民.旋覆花化学成分研究[J].中国现代应用药学,2011,28(4):330-334. |
| DENG Shuangbing,JIAN Xiaoyong,REN Qisheng,SONG Xinrong,YE Lianbao,ZOU Guomin.Chemical Constituents from Inula Japonica Thunb[J].Chin J Mod Appl Pharm(中国现代应用药学),2011,28(4):330-334. |
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| 摘要: |
| 目的 研究旋覆花Inula japonica Thunb.的化学成分。方法 采用多种分离技术对旋覆花乙醇提取物的氯仿和乙酸乙酯萃取部分分离纯化，根据其理化常数测定和光谱数据进行结构鉴定。结果 从旋覆花中分得11个化合物，经鉴定为金圣草素(Ⅰ)，万寿菊素(Ⅱ)，槲皮素(Ⅲ)，木犀草素(Ⅳ)，山奈酚(Ⅴ)，旋覆花内酯C(Ⅵ)，旋覆花内酯(Ⅶ)，胡萝卜苷(Ⅷ)，β-谷甾醇(Ⅸ)，大花旋覆花内酯(Ⅹ)，ivangustin(Ⅺ)。结论 化合物Ⅰ为首次从欧亚旋覆花植物中得到。 |
| 关键词: 旋覆花 化学成分 提取分离 结构鉴定 光谱技术 |
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| Chemical Constituents from Inula Japonica Thunb |
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DENG Shuangbing1,2, JIAN Xiaoyong1, REN Qisheng3, SONG Xinrong3, YE Lianbao2, ZOU Guomin4
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1.Zhendong Guangming Medicine Research Institute Co., Ltd, Beijing 100120, China;2.Faculty of Pharmaceutical Science, Guangdong Pharmaceutical University, Guangzhou 510006, China;3.Jiangzhong Zesheng Technology Co. Ltd., Beijing 100034, China;4.Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
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| Abstract: |
| OBJECTIVE To study the chemical constituents in Inula japonica Thunb. METHODS A variety of separation technologies were used for the isolation of compounds, and their structures were identified by physical properties and spectroscopic techniques (NMR, IR, UV and MS). RESULTS Eleven compounds, chrysoeriol(Ⅰ), patuletin(Ⅱ), quercetin(Ⅲ), luteolin(Ⅳ), kaempferol(Ⅴ), inuchinenolide C(Ⅵ), britannilactone(Ⅶ), daucosterol(Ⅷ), β-sitosterol(Ⅸ), britanin(Ⅹ) and ivangustin(Ⅺ), were obtained from Inula japonica Thunb. CONCLUSION Compound Ⅰ was isolated from this genus for the first time. |
| Key words: Inula japonica Thunb chemical constituents extraction and separation identification spectroscopic techniques |
